Motigut 10mg | Domperidone | Uses, Dosage, Side Effects | ePharma
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Motigut 10mg Tablet

Generic: Domperidone 10 mg

Type: Tablet

Pack Size: 10pcs

Motigut 10 is a prescription medication that is used to treat indigestion, nausea, and vomiting. It inhibits the substance in the brain that causes nausea or vomiting, as well as increases the movement of food in the stomach, which improves digestion.


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MRP: ৳ 35 6% Off

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✅ Description:

  • Motigut 10 Tablet is an effective anti-emetic medication used to relieve nausea and vomiting caused by delayed gastric emptying. It works by increasing intestinal movements and facilitating bowel emptying. This medicine can be taken alone or with other medications to treat nausea, vomiting, and indigestion.
  • Possible side effects of Motigut 10 Tablet include headache, dry mouth, stomach pain, and dizziness. These are usually temporary and tend to resolve with time. If any symptoms persist, consult your doctor. Diarrhea may also occur, so staying hydrated with plenty of fluids is recommended.
  • Take Motigut 10 Tablet 30 minutes before meals, following your doctor's directions. Avoid this medicine if you have allergies to it and refrain from consuming alcohol during treatment, as it can worsen side effects.
  • This medication is not suitable for children below 12 years due to limited safety data. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before taking Motigut 10 Tablet. If you have liver, kidney, or gastrointestinal bleeding issues, consult your doctor before use.

Safety Advices


Alcohol
CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Motigut 10. Please consult your doctor.


Pregnancy
CONSULT YOUR DOCTOR

Motigut 10 may be harmful to a pregnant woman. Although there have been few human studies, animal studies have revealed harmful effects on the developing baby. Before prescribing it to you, your doctor will consider the benefits as well as any potential risks. Please consult your physician.


Breastfeeding
SAFE IF PRESCRIBED

Motigut 10 is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Driving
UNSAFE

Motigut 10 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.


Kidney
CAUTION

Motigut 10 should be used with caution in patients with kidney disease. A dose adjustment of Motigut 10 may be needed. Please consult your doctor.


Liver
CAUTION

Motigut 10 should be used with caution in patients with liver disease. Dose adjustment of Motigut 10 may be needed. Please consult your doctor. Use of Motigut 10 is not recommended in patients with moderate and severe liver disease.

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✔️ Uses of Motigut 10
  • Indigestion
  • Nausea
  • Vomiting
✔️ Side effects of Motigut 10
  • Extrapyramidal effects
  • Drowsiness
  • Galactorrhea,
  • Gynecomastia
  • Constipation or diarrhea
  • Lethargy, loss of libido
  • Skin rash, and itching
  • Convulsions
  • Arrhythmias and cardiac arrest,
  • Dysrhythmias in people with cardiovascular disease or hypokalemia
  • and people receiving chemotherapy for cancer are all potentially fatal. seizures and hypertensive crises in pheochromocytoma patients.
✔️ Quick Suggestions:
  • Motigut 10 aids in the relief of nausea, vomiting, and indigestion.
  • It should be taken before meals, according to your doctor's instructions.
  • In adults and adolescents 12 years of age and older with a body weight of 35kg or more, domperidone should be used at the lowest effective dose.
  •  
  • It can make you dizzy and sleepy. Do not drive or engage in any activity that requires mental focus until you have determined how it affects you.
  • When taking Motigut 10, avoid drinking alcohol as it may cause excessive drowsiness.
  • As a side effect, dry mouth is possible. Frequent mouth rinses, good oral hygiene, increased water consumption, and sugarless candy may be beneficial.
  • Inform your doctor if you develop watery diarrhea, a fever, or persistent stomach pain.
  • Contact your doctor if you have palpitations, difficulty breathing, or loss of consciousness while taking this medication. Domperidone treatment should be discontinued. Without consulting your doctor, do not take it for more than 7 days.
✔️ Indications

Motigut is an antiemetic and prokinetic medication. It belongs to a class of drugs known as dopamine antagonists. It is used to treat stomach problems such as nausea and vomiting, as well as stomach pain and discomfort caused by decreased stomach and upper gastrointestinal (GI) tract movement. It is also used to increase the supply of breast milk.

✔️ Pharmacology

Motigut may be a dopamine antagonist that primarily targets the stomach's and the Chemoreceptor rigger Zone's (CTZ) dopamine receptors. Its gastroprokinetic function is dependent on the dopamine receptors it blocks, which affect gastrointestinal tract motility. Domperidone has a negligible effect on the dopaminergic receptors in the brain because of its inability to cross the blood-brain barrier; as a result, it has no psychotropic or neurologic adverse effects. Domperidone improves antral and duodenal peristalsis, restores normal upper gastrointestinal tract motility and tone, and inhibits pylorus withdrawal. It also promotes gastric purge. Domperidone also increases esophageal peristalsis and decreases the weight of the esophageal sphincter, preventing the release of gastric contents.

✔️ Dosage & Administration of Motigut 10

Motigut should be consumed 15 to 30 minutes after supper and, if necessary, just before retiring.

The regular suggested verbal dosage of Domperidone is as follows: 

  • Adults: 10–20 mg every 6–8 hours throughout the day (1-2 tablets or 10–20 ml solution). The highest dosage of Domperidone is 80 mg per day.
  • Children: every 6 to 8 hours, 2-4 ml suspension/10 kg body weight or 0.4 to 0.8 ml pediatric drops/10 kg body weight.

In Dyspeptic symptoms: 

  • Adults: 10–20 mg every 6–8 hours (1-2 tablets or 10–20 ml solution).
  • Children: every 6 to 8 hours, 0.2 to 0.4 mg/kg (2-4 ml suspension/10 kg or 0.4 to 0.8 ml pediatric drops/10 kg) body weight.

In intense and sub-acute conditions (primarily in intense sickness and vomiting): 

  • Adults: twice daily, every 6 to 8 hours, 20 mg (2 tablets or 20 ml suspension).
  • Children: every 6 to 8 hours, 0.2 to 0.4 mg/kg (2-4 ml suspension/10 kg or 0.4 to 0.8 ml pediatric drops/10 kg) body weight. The most extreme treatment term for severe nausea and vomiting is 12 weeks.

Renal Dose

  • Mild to moderate kidney impairment: No dosage adjustment needed. Severe: With prolonged treatment, reduce dosing to 1-2 times daily.
✔️ How to use Motigut 10
  • Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole.
  • Do not chew, crush or break it.
  • Motigut 10 is to be taken empty stomach.
✔️ How Motigut 10 works

Motigut 10 is a prokinetic. It works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.

✔️ What if you forget to take Motigut 10?

If you miss a dose of Motigut 10, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

✔️ Interaction

The risk of bromocriptine's hypoprolactemic effects may be reduced by Motigut. Antimuscarinics and opioid analgesics may counteract Motigut's activity on Gl work. When domperidone is used in conjunction with MAO (monoamine oxidase) inhibitors, caution should be taken.

✔️ Contraindications

Neonatal patients and those with documented high sensitivity to this sedative should not use Motigut. When gastrointestinal stimulation can be dangerous, such as when it results in gastrointestinal hemorrhage, mechanical obstruction, or puncturing, domperidone shouldn't be taken. Too dangerous for people with prolactin-releasing pituitary tumors (prolactinoma).

✔️ Pregnancy & Lactation

The security of domperidone has not been demonstrated and it is in this manner not suggested amid pregnancy. The creature thinks about has not illustrated the teratogenic impact within the embryo. Motigut may accelerate galactorrhea and move forward post-natal lactation. It is emitted in breast drain but in exceptionally little amounts deficiently to be considered destructive.

✔️ Precautions & Warnings
  • Motigut should be used with extreme caution when treating children because extrapyramidal reactions may be more likely in young children due to an incompletely formed blood-brain barrier.
  • Since domperidone is exceedingly metabolized in the liver, it ought to be utilized with caution in understanding hepatic disability.
✔️ Storage Conditions

Store below 30°C, Secured from light & dampness. Keep out of children's reach.

Frequently Asked Questions (FAQ)

Motigut is primarily used to treat nausea and vomiting associated with various conditions, including GERD, gastroparesis, and chemotherapy. In some countries, it is also used to increase milk production in breastfeeding women.

If you take too much domperidone, seek medical attention straight away.

Yes, domperidone can interact with other medications. It should be used with caution in people taking certain medications, such as antifungal agents and antibiotics. It is important to speak with a healthcare provider about potential drug interactions before taking domperidone.

Motigut works by blocking dopamine receptors in the brain and gastrointestinal tract. This action helps increase the movement of food through the stomach and intestines, which can reduce nausea and vomiting.

Yes, this medicine should be taken on an empty stomach.

Motigut is taken on an as-needed basis, and the dose and frequency may vary among individuals depending on their specific underlying condition. It is important not to exceed the prescribed daily dose as advised by the doctor.
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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